|
KMID : 0043320130360101211
|
|
Archives of Pharmacal Research
2013 Volume.36 No. 10 p.1211 ~ p.1214
|
|
|
Cytotoxic lignans from Viburnum foetidum
|
|
Li Hong
Luo Yuanguo
Ma Yan
Zeng Jun
Zhang Xu
Wang Dong
Hu Chunlin
|
|
|
Abstract
|
|
|
|
Two new lignans, 3,4,4′-trihydroxy-3′,9-dimethoxy-9,9′-epoxylignan (1), 3,4′-dihydroxy-3′,4, 9-trimethoxy-9,9′-epoxylignan (2), together with one known compound, 4,4′-dihydroxy-3,3′,9-trimethoxy-9,9′-epoxylignan (3), were isolated from the 95 % EtOH extract of Viburnum foetidum. The structures of the two new compounds were elucidated on the basis of 1D, 2D-NMR, and mass spectral analysis. All the lignans were in vitro evaluated for their cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15).
|
|
|
KEYWORD
|
|
|
Viburnum foetidum, Caprifliaceae, Lignans, Cytotoxicity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|